Changes in version 1.14.0 (2020-10-28)                 

    o   Add the splatPop simulation. This is a extension to the splat
	simulation contributed by Christina Azodi and Davis McCarthy
	that adds population effects. It allows you to specify
	relatedness between individuals and generate cell-type specific
	eQTL effects.

    o   Add a batch.rmEffect parameter to the Splat simulation. This
	allows generation of a paired simulation without any batch
	effects.

    o   Add a new minimiseSCE function which can be used to remove
	unneeded information from simulation output (or any
	SingleCellExperiment)

    o   All simulations now return sparse assay matrices by default
	when they would be smaller than the equivalent dense matrix.
	This is controlled by a new sparsify argument.

    o   Users will now be automatically prompted to install packages if
	they try to use a simulation for which the suggested
	dependencies are not available

                 Changes in version 1.12.0 (2020-04-20)                 

    o   Add checks for cycles in the Splat path.from parameter.

    o   Use alternative algorithm if fitting dropout fails in
	splatEstimate.

    o   Adjust paths example in vignette.

    o   Replace defunct functions in vignettes.

    o   Minor fixes for compatibility with updates to other packages.

                 Changes in version 1.10.0 (2019-10-20)                 

    o   Add the (experimental) Kersplat simulation model. This model
	incorporates a gene network and other useful features.

    o   Refactor the summariseDiff function and add the KS statistic.

    o   Add variable gene correlation plot to compareSCEs and violins
	to other comparison plots.

    o   Check for counts assay when estimating from
	SingleCellExperiment objects.

    o   Fix where simpleSimulate stores parameters.

    o   Fix bugs where parameters were not being passed correctly in
	BASiCSEstimate and sparseDCEstimate.

    o   Replace the sc_example_counts dataset from scater with the
	mockSCE function.

    o   Tidy and improve estimation function examples and add checks
	for suggested packages.

    o   Various fixes for compatibility with updates to other packages.

                 Changes in version 1.8.0 (2019-04-18)                  

    o   Add a Splat parameters vignette

    o   Rename the Splat path.length parameter to path.nSteps

    o   Fix a bug with parameter order in setParams

    o   Fix a bug where Splat groups were being simulated in
	alphanumeric order

    o   Protect against integer overflow in simulation functions

                 Changes in version 1.6.0 (2018-10-29)                  

    o   Fix bug and improve normality testing in splatEstLib

    o   Fixes for compatibility with the latest version of BASiCS,
	BASiCSEstimate now uses the regression method

    o   Fix bug in getLNormFactors when reversing factors less than one

    o   Various updates to tests and documentation

                 Changes in version 1.3.5 (2018-04-25)                  

    o   Move scater to Imports and add scater version

    o   Remove lingering references to SCESets

    o   Add option to use a normal distribution for library sizes in
	Splat simulations

    o   Allow Splat dropout parameters to be specified by experiment,
	batch, group or cell

    o   Add SparseDC simulation

    o   Rename params in metadata slot of simulation to Params for
	consistency

    o   Improve and colourise Params print output

    o   Improve test coverage

    o   Various other minor updates and bug fixes

                 Changes in version 1.1.8 (2017-10-13)                  

    o   Now published in Genome Biology!

    o   Converted to the SingleCellExperiment object

    o   Added new simulations: BASiCS, mfa, PhenoPath, ZINB-WaVE

    o   Added batch effects to the Splat simulation. This required a
	change to the SplatParams object.

    o   Improved scDD estimation

    o   Added and improved comparison functions

    o   Improved default Splat parameters and estimation

    o   Improvements to the Lun2Params object

    o   Added addGeneLength function

    o   Updated simulation references

    o   Various other minor updates and bug fixes

                Changes in version 0.99.16 (2017-04-23)                 

    o   Splatter is a package for the simple simulation of single-cell
	RNA-seq data, including:

    o   Multiple simulation models

    o   Parameter estimation from real data

    o   Functions for comparing simulations and real datasets

    o   Simulation of complex groups and differentiation paths

                 Changes in version 0.99.0 (2016-12-05)                 

    o   Package prepared for Bioconductor submission.