Package: MeLSI
Type: Package
Title: Metric Learning for Statistical Inference in Microbiome Analysis
Version: 0.99.9
Authors@R: c(person("Nathan", "Bresette", email = "nathanbresette04@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0009-0003-1554-6006")), person("Aaron C.", "Ericsson", role = "aut", comment = c(ORCID = "0000-0002-3053-7269")), person("Carter", "Woods", role = "aut", comment = c(ORCID = "0009-0007-5345-2712")), person("Ai-Ling", "Lin", role = c("aut", "fnd"), comment = c(ORCID = "0000-0002-5197-2219")))
Description: MeLSI (Metric Learning for Statistical Inference) is a novel machine learning method for microbiome data analysis that learns optimal distance metrics to improve statistical power in detecting group differences. Unlike traditional distance metrics (Bray-Curtis, Euclidean, Jaccard), MeLSI adapts to the specific characteristics of your dataset to maximize separation between groups. The method uses an ensemble of weak learners to identify which microbial features drive group differences, providing both improved statistical power and biological interpretability through feature importance weights.
License: MIT + file LICENSE
Encoding: UTF-8
RoxygenNote: 7.3.3
Depends: R (>= 4.5.0)
URL: https://github.com/NathanBresette/MeLSI
BugReports: https://github.com/NathanBresette/MeLSI/issues
Imports: vegan, ggplot2, phyloseq, stats, utils
Suggests: testthat, knitr, rmarkdown, BiocManager, BiocStyle,
        BiocParallel, Matrix, microbiome
VignetteBuilder: knitr
biocViews: Software, StatisticalMethod, Microbiome
git_url: https://git.bioconductor.org/packages/MeLSI
git_branch: devel
git_last_commit: dd590e4
git_last_commit_date: 2026-04-17
Repository: Bioconductor 3.24
Date/Publication: 2026-04-20
NeedsCompilation: no
Packaged: 2026-04-20 23:14:24 UTC; biocbuild
Author: Nathan Bresette [aut, cre] (ORCID:
    <https://orcid.org/0009-0003-1554-6006>),
  Aaron C. Ericsson [aut] (ORCID:
    <https://orcid.org/0000-0002-3053-7269>),
  Carter Woods [aut] (ORCID: <https://orcid.org/0009-0007-5345-2712>),
  Ai-Ling Lin [aut, fnd] (ORCID: <https://orcid.org/0000-0002-5197-2219>)
Maintainer: Nathan Bresette <nathanbresette04@gmail.com>
