tspair

Top Scoring Pairs for Microarray Classification

Bioconductor version: Development (2.8)

These functions calculate the pair of genes that show the maximum difference in ranking between two user specified groups. This "top scoring pair" maximizes the average of sensitivity and specificity over all rank based classifiers using a pair of genes in the data set. The advantage of classifying samples based on only the relative rank of a pair of genes is (a) the classifiers are much simpler and often more interpretable than more complicated classification schemes and (b) if arrays can be classified using only a pair of genes, PCR based tests could be used for classification of samples. See the references for the tspcalc() function for references regarding TSP classifiers.

Author: Jeffrey T. Leek

Maintainer: Jeffrey T. Leek

To install this package, start R and enter:

source("http:///biocLite.R")
biocLite("tspair")    

Documentation

PDF		tsp1.pdf
PDF	R Script	tspTutorial

Reference Manual

Details

biocViews	Microarray, Bioinformatics
Depends	R, Biobase, time
Imports
Suggests
System Requirements
License	GPL-2
URL
Depends On Me
Imports Me
Suggests Me
Version	1.9.1

Package Downloads

Package Source	tspair_1.9.1.tar.gz
Windows Binary	tspair_1.9.1.zip (32- & 64-bit)
MacOS 10.5 (Leopard) binary	tspair_1.9.1.tgz
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