Bioconductor 3.23 Release Schedule

immLynx

This is the development version of immLynx; to use it, please install the devel version of Bioconductor.

Linking Advanced TCR Python Pipelines and Hugging Face Models in R


Bioconductor version: Development (3.23)

A comprehensive toolkit that bridges popular Python-based immune repertoire analysis tools and Hugging Face protein language models into the R environment. Provides unified interfaces for TCR distance calculations (tcrdist3), sequence generation probability (OLGA), selection inference (soNNia), clustering (clusTCR), protein embeddings (ESM-2), metaclone discovery (metaclonotypist). Fully compatible with the scRepertoire and immApex ecosystem for single-cell immune repertoire analysis.

Author: Nick Borcherding [aut, cre] ORCID iD ORCID: 0000-0003-1427-6342

Maintainer: Nick Borcherding <ncborch at gmail.com>

Citation (from within R, enter citation("immLynx")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("immLynx")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("immLynx")
Advanced TCR Analysis with immLynx HTML R Script
Getting Started with immLynx HTML R Script
Reference Manual PDF

Details

biocViews Annotation, Classification, Clustering, DimensionReduction, ImmunoOncology, MotifAnnotation, Sequencing, SingleCell, Software
Version 0.99.4
In Bioconductor since BioC 3.23 (R-4.6)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports basilisk(>= 1.8.0), reticulate (>= 1.24), immApex, methods, S4Vectors, SingleCellExperiment, stats, SummarizedExperiment, utils
System Requirements
URL https://github.com/BorchLab/immLynx/
Bug Reports https://github.com/BorchLab/immLynx/issues
See More
Suggests BiocStyle, ggplot2, knitr, markdown, rmarkdown, scater, scran, scRepertoire, spelling, testthat (>= 3.0.0), withr
Linking To
Enhances
Depends On Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package immLynx_0.99.4.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64)
macOS Binary (big-sur-arm64)
macOS Binary (sonoma-arm64) immLynx_0.99.4.tgz
Source Repository git clone https://git.bioconductor.org/packages/immLynx
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/immLynx
Bioc Package Browser https://code.bioconductor.org/browse/immLynx/
Package Short Url https://bioconductor.org/packages/immLynx/
Package Downloads Report Download Stats