Multiple platform build/check report for BioC 3.21 - CHECK results for decoupleR on lconway

Hostname	OS	Arch (*)	R version	Installed pkgs
nebbiolo1	Linux (Ubuntu 24.04.1 LTS)	x86_64	R Under development (unstable) (2025-03-13 r87965) -- "Unsuffered Consequences"	4742
palomino7	Windows Server 2022 Datacenter	x64	R Under development (unstable) (2025-03-01 r87860 ucrt) -- "Unsuffered Consequences"	4545
lconway	macOS 12.7.1 Monterey	x86_64	R Under development (unstable) (2025-03-02 r87868) -- "Unsuffered Consequences"	4576
kjohnson3	macOS 13.7.1 Ventura	arm64	R Under development (unstable) (2025-03-02 r87868) -- "Unsuffered Consequences"	4528
kunpeng2	Linux (openEuler 24.03 LTS)	aarch64	R Under development (unstable) (2025-02-19 r87757) -- "Unsuffered Consequences"	4459
Click on any hostname to see more info about the system (e.g. compilers) () as reported by 'uname -p', except on Windows and Mac OS X*

CHECK results for decoupleR on lconway

To the developers/maintainers of the decoupleR package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/decoupleR.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.

raw results

Summary

Package: decoupleR

Version: 2.13.0

Command: /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:decoupleR.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings decoupleR_2.13.0.tar.gz

StartedAt: 2025-03-18 20:18:28 -0400 (Tue, 18 Mar 2025)

EndedAt: 2025-03-18 20:27:36 -0400 (Tue, 18 Mar 2025)

EllapsedTime: 547.2 seconds

RetCode: 0

Status: WARNINGS

CheckDir: decoupleR.Rcheck

Warnings: 1

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:decoupleR.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings decoupleR_2.13.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/Users/biocbuild/bbs-3.21-bioc/meat/decoupleR.Rcheck’
* using R Under development (unstable) (2025-03-02 r87868)
* using platform: x86_64-apple-darwin20
* R was compiled by
    Apple clang version 14.0.0 (clang-1400.0.29.202)
    GNU Fortran (GCC) 14.2.0
* running under: macOS Monterey 12.7.6
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘decoupleR/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘decoupleR’ version ‘2.13.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘decoupleR’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... NOTE
[2025-03-18 20:19:10] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:19:10] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:19:10] [INFO]    [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-03-18 20:19:10] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-03-18 20:19:10] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-03-18
[2025-03-18 20:19:10] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-03-18 19:09:53 UTC; unix
[2025-03-18 20:19:10] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.15.11
[2025-03-18 20:19:10] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-03-18 20:19:10] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-03-02 r87868); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-03-18; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=NA]
[2025-03-18 20:19:10] [INFO]    [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.0]
[2025-03-18 20:19:11] [INFO]    [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); annotate 1.85.0(2025-03-18); AnnotationDbi 1.69.0(2025-03-18); AUCell 1.29.0(2025-03-18); backports 1.5.0(2024-05-23); beachmat 2.23.7(2025-03-18); Biobase 2.67.0(2025-03-18); BiocGenerics 0.53.6(2025-03-18); BiocParallel 1.41.2(2025-03-18); BiocSingular 1.23.0(2025-03-18); Biostrings 2.75.4(2025-03-18); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); chromote 0.4.0(2025-01-25); cli 3.6.4(2025-02-13); codetools 0.2-20(2024-03-31); crayon 1.5.3(2024-06-20); curl 6.2.1(2025-02-19); data.table 1.17.0(2025-02-22); DBI 1.2.3(2024-06-02); decoupleR 2.13.0(2025-03-18); DelayedArray 0.33.6(2025-03-18); DelayedMatrixStats 1.29.1(2025-03-18); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fs 1.6.5(2024-10-30); generics 0.1.3(2022-07-05); GenomeInfoDb 1.43.4(2025-03-18); GenomeInfoDbData 1.2.14(2025-03-12); GenomicRanges 1.59.1(2025-03-18); glue 1.8.0(2024-09-30); graph 1.85.2(2025-03-18); GSEABase 1.69.1(2025-03-18); GSVA 2.1.8(2025-03-18); h5mread 0.99.4(2025-03-18); HDF5Array 1.35.15(2025-03-18); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.1.1(2025-03-08); igraph 2.1.4(2025-01-23); IRanges 2.41.3(2025-03-18); irlba 2.3.5.1(2022-10-03); jsonlite 1.9.1(2025-03-03); KEGGREST 1.47.0(2025-03-18); knitr 1.50(2025-03-16); later 1.4.1(2024-11-27); lattice 0.22-6(2024-03-20); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magick 2.8.5(2024-09-20); magrittr 2.0.3(2022-03-30); Matrix 1.7-3(2025-03-11); MatrixGenerics 1.19.1(2025-03-18); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); OmnipathR 3.15.11(2025-03-18); parallelly 1.42.0(2025-01-30); pillar 1.10.1(2025-01-07); pkgconfig 2.0.3(2019-09-22); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.2(2024-11-28); ps 1.9.0(2025-02-18); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rhdf5 2.51.2(2025-03-18); rhdf5filters 1.19.2(2025-03-18); Rhdf5lib 1.29.1(2025-03-18); rjson 0.2.23(2024-09-16); rlang 1.1.5(2025-01-17); rmarkdown 2.29(2024-11-04); RSQLite 2.3.9(2024-12-03); rsvd 1.0.5(2021-04-16); rvest 1.0.4(2024-02-12); S4Arrays 1.7.3(2025-03-18); S4Vectors 0.45.4(2025-03-18); ScaledMatrix 1.15.0(2025-03-18); sessioninfo 1.2.3(2025-02-05); SingleCellExperiment 1.29.2(2025-03-18); SparseArray 1.7.6(2025-03-18); sparseMatrixStats 1.19.0(2025-03-18); SpatialExperiment 1.17.0(2025-03-18); stringi 1.8.4(2024-05-06); stringr 1.5.1(2023-11-14); SummarizedExperiment 1.37.0(2025-03-18); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); UCSC.utils 1.3.1(2025-03-18); vctrs 0.6.5(2023-12-01); websocket 1.4.2(2024-07-22); withr 3.0.2(2024-10-28); xfun 0.51(2025-02-19); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); xtable 1.8-4(2019-04-21); XVector 0.47.2(2025-03-18); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-03-18 20:19:11] [INFO]    [OmnipathR] CURL: version: 8.11.1; headers: 8.11.1; ssl_version: OpenSSL/3.3.2 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Contains 8 files.
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:19:11] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Pandoc version: `2.7.3`.
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:19:11] [TRACE]   [OmnipathR] Cache locked: FALSE
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... WARNING
Missing link(s) in Rd file 'run_gsva.Rd':
  ‘GSVA::gsva’ ‘GeneSetCollection’

See section 'Cross-references' in the 'Writing R Extensions' manual.

Found the following Rd file(s) with Rd \link{} targets missing package
anchors:
  run_gsva.Rd: GSVA::gsva, GeneSetCollection
Please provide package anchors for all Rd \link{} targets not in the
package itself and the base packages.
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                user system elapsed
get_dorothea  25.954  1.994  31.030
run_fgsea     20.953  1.319  22.579
run_aucell    12.152  4.511  16.731
get_collectri  8.993  1.241  19.038
get_progeny    5.905  0.701  29.288
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 1 WARNING, 1 NOTE
See
  ‘/Users/biocbuild/bbs-3.21-bioc/meat/decoupleR.Rcheck/00check.log’
for details.

Installation output

decoupleR.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL decoupleR
###
##############################################################################
##############################################################################


* installing to library ‘/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library’
* installing *source* package ‘decoupleR’ ...
** this is package ‘decoupleR’ version ‘2.13.0’
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
*** copying figures
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (decoupleR)

Tests output

decoupleR.Rcheck/tests/testthat.Rout


R Under development (unstable) (2025-03-02 r87868) -- "Unsuffered Consequences"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin20

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(testthat)
> library(decoupleR)
> 
> test_check("decoupleR")

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[2025-03-18 20:23:11] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:11] [INFO]    [OmnipathR] Initialized cache: `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-03-18 20:23:11] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-03-18 20:23:11] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-03-18
[2025-03-18 20:23:11] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-03-18 19:09:53 UTC; unix
[2025-03-18 20:23:11] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.15.11
[2025-03-18 20:23:11] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-03-18 20:23:12] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-03-02 r87868); os=macOS Monterey 12.7.6; system=x86_64, darwin20; ui=X11; language=C; collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-03-18; pandoc=2.7.3 @ /usr/local/bin/ (via rmarkdown); quarto=NA]
[2025-03-18 20:23:12] [INFO]    [OmnipathR] External libraries: [cairo=1.17.6; cairoFT=; pango=1.50.14; png=1.6.44; jpeg=9.5; tiff=LIBTIFF, Version 4.5.0; tcl=8.6.13; curl=8.7.1; zlib=1.2.11; bzlib=1.0.8, 13-Jul-2019; xz=5.6.3; deflate=1.23; PCRE=10.44 2024-06-07; ICU=70.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=Apple or GNU libiconv 1.11 /Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libR.dylib; readline=5.2; BLAS=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRblas.0.dylib; lapack=/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/lib/libRlapack.dylib; lapack_version=3.12.0]
[2025-03-18 20:23:12] [INFO]    [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); annotate 1.85.0(2025-03-18); AnnotationDbi 1.69.0(2025-03-18); AUCell 1.29.0(2025-03-18); backports 1.5.0(2024-05-23); beachmat 2.23.7(2025-03-18); Biobase 2.67.0(2025-03-18); BiocGenerics 0.53.6(2025-03-18); BiocParallel 1.41.2(2025-03-18); BiocSingular 1.23.0(2025-03-18); Biostrings 2.75.4(2025-03-18); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); brio 1.1.5(2024-04-24); broom 1.0.7(2024-09-26); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); chromote 0.4.0(2025-01-25); class 7.3-23(2025-01-01); cli 3.6.4(2025-02-13); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); cowplot 1.1.3(2024-01-22); crayon 1.5.3(2024-06-20); curl 6.2.1(2025-02-19); data.table 1.17.0(2025-02-22); DBI 1.2.3(2024-06-02); decoupleR 2.13.0(2025-03-18); DelayedArray 0.33.6(2025-03-18); DelayedMatrixStats 1.29.1(2025-03-18); desc 1.4.3(2023-12-10); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); e1071 1.7-16(2024-09-16); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fastmatch 1.1-6(2024-12-23); fgsea 1.33.2(2025-03-18); fs 1.6.5(2024-10-30); generics 0.1.3(2022-07-05); GenomeInfoDb 1.43.4(2025-03-18); GenomeInfoDbData 1.2.14(2025-03-12); GenomicRanges 1.59.1(2025-03-18); ggplot2 3.5.1(2024-04-23); glue 1.8.0(2024-09-30); graph 1.85.2(2025-03-18); GSEABase 1.69.1(2025-03-18); GSVA 2.1.8(2025-03-18); gtable 0.3.6(2024-10-25); h5mread 0.99.4(2025-03-18); HDF5Array 1.35.15(2025-03-18); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httr 1.4.7(2023-08-15); httr2 1.1.1(2025-03-08); igraph 2.1.4(2025-01-23); IRanges 2.41.3(2025-03-18); irlba 2.3.5.1(2022-10-03); jsonlite 1.9.1(2025-03-03); KEGGREST 1.47.0(2025-03-18); kernlab 0.9-33(2024-08-13); KernSmooth 2.23-26(2025-01-01); knitr 1.50(2025-03-16); later 1.4.1(2024-11-27); lattice 0.22-6(2024-03-20); lazyeval 0.2.2(2019-03-15); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magick 2.8.5(2024-09-20); magrittr 2.0.3(2022-03-30); MASS 7.3-65(2025-02-28); Matrix 1.7-3(2025-03-11); MatrixGenerics 1.19.1(2025-03-18); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); mixtools 2.0.0.1(2025-03-08); munsell 0.5.1(2024-04-01); nlme 3.1-167(2025-01-27); OmnipathR 3.15.11(2025-03-18); parallelly 1.42.0(2025-01-30); pillar 1.10.1(2025-01-07); pkgconfig 2.0.3(2019-09-22); plotly 4.10.4(2024-01-13); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.2(2024-11-28); proxy 0.4-27(2022-06-09); ps 1.9.0(2025-02-18); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); ranger 0.17.0(2024-11-08); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rhdf5 2.51.2(2025-03-18); rhdf5filters 1.19.2(2025-03-18); Rhdf5lib 1.29.1(2025-03-18); rjson 0.2.23(2024-09-16); rlang 1.1.5(2025-01-17); rmarkdown 2.29(2024-11-04); rpart 4.1.24(2025-01-07); RSQLite 2.3.9(2024-12-03); rsvd 1.0.5(2021-04-16); rvest 1.0.4(2024-02-12); S4Arrays 1.7.3(2025-03-18); S4Vectors 0.45.4(2025-03-18); ScaledMatrix 1.15.0(2025-03-18); scales 1.3.0(2023-11-28); segmented 2.1-4(2025-02-28); sessioninfo 1.2.3(2025-02-05); SingleCellExperiment 1.29.2(2025-03-18); SparseArray 1.7.6(2025-03-18); sparseMatrixStats 1.19.0(2025-03-18); SpatialExperiment 1.17.0(2025-03-18); stringi 1.8.4(2024-05-06); stringr 1.5.1(2023-11-14); SummarizedExperiment 1.37.0(2025-03-18); survival 3.8-3(2024-12-17); testthat 3.2.3(2025-01-13); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); UCSC.utils 1.3.1(2025-03-18); vctrs 0.6.5(2023-12-01); viper 1.41.0(2025-03-18); viridisLite 0.4.2(2023-05-02); waldo 0.6.1(2024-11-07); websocket 1.4.2(2024-07-22); withr 3.0.2(2024-10-28); xfun 0.51(2025-02-19); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); xtable 1.8-4(2019-04-21); XVector 0.47.2(2025-03-18); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-03-18 20:23:12] [INFO]    [OmnipathR] CURL: version: 8.11.1; headers: 8.11.1; ssl_version: OpenSSL/3.3.2 (SecureTransport); libz_version: 1.2.11; libssh_version: NA; libidn_version: NA; host: x86_64-apple-darwin22.6.0; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, smb, smbs, smtp, smtps, telnet, tftp, ws, wss; ipv6: TRUE; http2: TRUE; idn: FALSE; url_parser: TRUE
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Cache is at `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Contains 8 files.
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:12] [SUCCESS] [OmnipathR] Removing all cache contents from `/Users/biocbuild/Library/Caches/OmnipathR`.
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Pandoc version: `2.7.3`.
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Reading JSON from `/Library/Frameworks/R.framework/Versions/4.5-x86_64/Resources/library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:12] [TRACE]   [OmnipathR] Cache locked: FALSE
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:14] [INFO]    [OmnipathR] Loading database `Ensembl and OMA organism names`.
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:14] [INFO]    [OmnipathR] Looking up in cache `https://www.ensembl.org/info/about/species.html`: key=7332486db7400730697234bad76ca0c8e4d00799, no version available.
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:14] [INFO]    [OmnipathR] Created new version for cache record 7332486db7400730697234bad76ca0c8e4d00799: version 1.
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Cache file path: /Users/biocbuild/Library/Caches/OmnipathR/7332486db7400730697234bad76ca0c8e4d00799-1.html
[2025-03-18 20:23:14] [INFO]    [OmnipathR] Retrieving URL: `https://www.ensembl.org/info/about/species.html`
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Downloading by `httr2` in `download_base`.
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Attempt 1/3: `https://www.ensembl.org/info/about/species.html`
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`.
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0]
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:134.0) Gecko/20100101 Firefox/134.0]
[2025-03-18 20:23:14] [TRACE]   [OmnipathR] Sending HTTP request.
[2025-03-18 20:23:15] [TRACE]   [OmnipathR] HTTP 200 (OK)
[2025-03-18 20:23:16] [TRACE]   [OmnipathR] Downloaded 31 Kb in 1.043973s from www.ensembl.org (29.7 Kb/s); Redirect: 0.873727s, DNS look up: 0.002345s, Connection: 0.004765s, Pretransfer: 0.743241s, First byte at: 1.018221s
[2025-03-18 20:23:16] [TRACE]   [OmnipathR] Response headers: [date=Wed, 19 Mar 2025 00:23:16 GMT,content-type=text/html; charset=utf-8,content-length=31787,server=Apache,set-cookie=redirect_mirror=; path=/; expires=Mon, 01-Jan-2001 00:00:01 GMT,set-cookie=redirect_mirror=no; path=/; expires=Thu, 20 Mar 2025 00:13:19 GMT,set-cookie=ENSEMBL_WWW_SESSION=aeec0a3a964c4d5a0c83b56e6829261f048ae4c9715aa51e833d0421; path=/; expires=Thu, 31-Dec-2037 23:59:59 GMT; HttpOnly,set-cookie=redirect_mirror=; path=/; expires=Mon, 01-Jan-2001 00:00:01 GMT,set-cookie=redirect_mirror=no; path=/; expires=Thu, 20 Mar 2025 00:13:19 GMT,set-cookie=ENSEMBL_WWW_SESSION=aeec0a3a964c4d5a0c83b56e6829261f048ae4c9715aa51e833d0421; path=/; expires=Thu, 31-Dec-2037 23:59:59 GMT; HttpOnly,vary=Accept-Encoding,content-encoding=gzip,x-frame-options=SAMEORIGIN,content-security-policy=frame-ancestors 'self',x-nginx-machine=ip-10-25-25-69.us-east-2.compute.internal]
[2025-03-18 20:23:17] [INFO]    [OmnipathR] Download ready [key=7332486db7400730697234bad76ca0c8e4d00799, version=1]
[2025-03-18 20:23:17] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:17] [INFO]    [OmnipathR] Cache item `7332486db7400730697234bad76ca0c8e4d00799` version 1: status changed from `unknown` to `ready`.
[2025-03-18 20:23:17] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] Looking up in cache: `https://omabrowser.org/All/oma-species.txt`.
[2025-03-18 20:23:18] [INFO]    [OmnipathR] Cache record does not exist: `https://omabrowser.org/All/oma-species.txt`
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://omabrowser.org/All/oma-species.txt`.
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:18] [INFO]    [OmnipathR] Cache item `30e690cbb55dfc63b5903ab337f34ffc2f4be397` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`.
[2025-03-18 20:23:18] [INFO]    [OmnipathR] Retrieving URL: `https://omabrowser.org/All/oma-species.txt`
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] Attempt 1/3: `https://omabrowser.org/All/oma-species.txt`
[2025-03-18 20:23:18] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:23:19] [TRACE]   [OmnipathR] Downloaded 108 Kb in 0.968131s from omabrowser.org (111.6 Kb/s); Redirect: 0s, DNS look up: 0.001186s, Connection: 0.002214s, Pretransfer: 0.331372s, First byte at: 0.414401s
[2025-03-18 20:23:20] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`.
[2025-03-18 20:23:20] [INFO]    [OmnipathR] Download ready [key=30e690cbb55dfc63b5903ab337f34ffc2f4be397, version=1]
[2025-03-18 20:23:20] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:20] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:20] [INFO]    [OmnipathR] Cache item `30e690cbb55dfc63b5903ab337f34ffc2f4be397` version 1: status changed from `started` to `ready`.
[2025-03-18 20:23:20] [INFO]    [OmnipathR] Loaded database `Ensembl and OMA organism names`.
[2025-03-18 20:23:20] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:23:20] [TRACE]   [OmnipathR] Arguments for OmniPath query: [wide=TRUE,resources=TFcensus,query_type=annotations]
[2025-03-18 20:23:20] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-18 20:23:20] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:23:21] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:23:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:21] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-18 20:23:21] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-18 20:23:21] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-18 20:23:21] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-18 20:23:21] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-18 20:23:21] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-18 20:23:21] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-18 20:23:21] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:23:21] [TRACE]   [OmnipathR] Downloaded 29.2 Kb in 0.421894s from omnipathdb.org (69.1 Kb/s); Redirect: 0s, DNS look up: 0.001111s, Connection: 0.001996s, Pretransfer: 0.187683s, First byte at: 0.346535s
[2025-03-18 20:23:22] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-18 20:23:22] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:22] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:22] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:22] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:22] [INFO]    [OmnipathR] Cache item `6f000d9b5edd9832b1c28754d1c3d9449c1c7490` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:23:22] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/6f000d9b5edd9832b1c28754d1c3d9449c1c7490-1.rds`.
[2025-03-18 20:23:22] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/6f000d9b5edd9832b1c28754d1c3d9449c1c7490-1.rds`.
[2025-03-18 20:23:22] [INFO]    [OmnipathR] Download ready [key=6f000d9b5edd9832b1c28754d1c3d9449c1c7490, version=1]
[2025-03-18 20:23:22] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:22] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:22] [INFO]    [OmnipathR] Cache item `6f000d9b5edd9832b1c28754d1c3d9449c1c7490` version 1: status changed from `started` to `ready`.
[2025-03-18 20:23:22] [SUCCESS] [OmnipathR] Downloaded 3099 annotation records.
[2025-03-18 20:23:23] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:23:23] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:23] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:23:23] [TRACE]   [OmnipathR] Arguments for OmniPath query: [wide=TRUE,resources=PROGENy,query_type=annotations]
[2025-03-18 20:23:23] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-18 20:23:23] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:23:24] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:23:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:24] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:24] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:24] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:24] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:24] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:24] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:24] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:24] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:23:32] [TRACE]   [OmnipathR] Downloaded 8.9 Mb in 6.936592s from omnipathdb.org (1.3 Mb/s); Redirect: 0s, DNS look up: 0.001093s, Connection: 0.002187s, Pretransfer: 0.167812s, First byte at: 0.321038s
[2025-03-18 20:23:34] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:34] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:34] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:34] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:34] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:34] [INFO]    [OmnipathR] Cache item `3492392585ba05414edfae46801492076437d7e7` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:23:34] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/3492392585ba05414edfae46801492076437d7e7-1.rds`.
[2025-03-18 20:23:37] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/3492392585ba05414edfae46801492076437d7e7-1.rds`.
[2025-03-18 20:23:37] [INFO]    [OmnipathR] Download ready [key=3492392585ba05414edfae46801492076437d7e7, version=1]
[2025-03-18 20:23:37] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:37] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:37] [INFO]    [OmnipathR] Cache item `3492392585ba05414edfae46801492076437d7e7` version 1: status changed from `started` to `ready`.
[2025-03-18 20:23:37] [SUCCESS] [OmnipathR] Downloaded 700239 annotation records.
[2025-03-18 20:23:39] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:23:39] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:39] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:23:39] [TRACE]   [OmnipathR] Arguments for OmniPath query: [wide=TRUE,resources=PROGENy,query_type=annotations]
[2025-03-18 20:23:39] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-18 20:23:39] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:23:40] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:23:40] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:40] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:42] [TRACE]   [OmnipathR] Loaded data from RDS `/Users/biocbuild/Library/Caches/OmnipathR/3492392585ba05414edfae46801492076437d7e7-1.rds`.
[2025-03-18 20:23:42] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-18 20:23:42] [SUCCESS] [OmnipathR] Loaded 700239 annotation records from cache.
[2025-03-18 20:23:44] [INFO]    [OmnipathR] Loading database `Orthologous Matrix (OMA) gene pairs`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Looking up in cache: `https://omabrowser.org/All/oma-species.txt`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Loaded data from RDS `/Users/biocbuild/Library/Caches/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Looking up in cache: `https://omabrowser.org/All/oma-species.txt`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Loaded data from RDS `/Users/biocbuild/Library/Caches/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Looking up in cache: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`.
[2025-03-18 20:23:44] [INFO]    [OmnipathR] Cache record does not exist: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:23:44] [INFO]    [OmnipathR] Cache item `8f45b25c384d814c7de210e7ca40b7e35894e4f1` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/8f45b25c384d814c7de210e7ca40b7e35894e4f1-1.rds`.
[2025-03-18 20:23:44] [INFO]    [OmnipathR] Retrieving URL: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Attempt 1/3: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`
[2025-03-18 20:23:44] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:24:12] [TRACE]   [OmnipathR] Downloaded 1.1 Mb in 27.335202s from omabrowser.org (42.4 Kb/s); Redirect: 0s, DNS look up: 0.001043s, Connection: 0.002041s, Pretransfer: 0.331746s, First byte at: 25.67243s
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/8f45b25c384d814c7de210e7ca40b7e35894e4f1-1.rds`.
[2025-03-18 20:24:13] [INFO]    [OmnipathR] Download ready [key=8f45b25c384d814c7de210e7ca40b7e35894e4f1, version=1]
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:24:13] [INFO]    [OmnipathR] Cache item `8f45b25c384d814c7de210e7ca40b7e35894e4f1` version 1: status changed from `started` to `ready`.
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] ID translation table: from `uniprot_entry` to `uniprot`, using `uniprot`.
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Creating ID mapping table from `id` to `accession`, for organism 9606 (only reviewed: TRUE)
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Loading all UniProt records for organism 9606 (only reviewed: TRUE); fields: id,accession
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Looking up in cache: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`.
[2025-03-18 20:24:13] [INFO]    [OmnipathR] Cache record does not exist: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`.
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:24:13] [INFO]    [OmnipathR] Cache item `6558a1824894a625b8e3f80538cd3aa6e8a44379` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/6558a1824894a625b8e3f80538cd3aa6e8a44379-1.rds`.
[2025-03-18 20:24:13] [INFO]    [OmnipathR] Retrieving URL: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Attempt 1/3: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`
[2025-03-18 20:24:13] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:24:45] [TRACE]   [OmnipathR] Downloaded 128.7 Kb in 31.199103s from rest.uniprot.org (4.1 Kb/s); Redirect: 0s, DNS look up: 0.020669s, Connection: 0.021507s, Pretransfer: 0.548439s, First byte at: 1.375876s
[2025-03-18 20:24:46] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/6558a1824894a625b8e3f80538cd3aa6e8a44379-1.rds`.
[2025-03-18 20:24:46] [INFO]    [OmnipathR] Download ready [key=6558a1824894a625b8e3f80538cd3aa6e8a44379, version=1]
[2025-03-18 20:24:46] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:24:46] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:24:46] [INFO]    [OmnipathR] Cache item `6558a1824894a625b8e3f80538cd3aa6e8a44379` version 1: status changed from `started` to `ready`.
[2025-03-18 20:24:46] [SUCCESS] [OmnipathR] UniProt (rest.uniprot.org): downloaded 20417 records
[2025-03-18 20:24:46] [TRACE]   [OmnipathR] Translating complexes: 0 complexes in data.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] 0 complexes after removing the ones mapping to more than 1 items in target identifier space.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Translated 0 complexes to 0.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] 13774 rows before translation, 13774 uniprot_entry IDs in column `id_organism_a`.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] 13774 rows after translation; translated 13570 `uniprot_entry` IDs in column `id_organism_a` to 13570 `uniprot` IDs in column `id_organism_a`.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] ID translation table: from `uniprot_entry` to `uniprot`, using `uniprot`.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Creating ID mapping table from `id` to `accession`, for organism 10090 (only reviewed: TRUE)
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Loading all UniProt records for organism 10090 (only reviewed: TRUE); fields: id,accession
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Looking up in cache: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`.
[2025-03-18 20:24:47] [INFO]    [OmnipathR] Cache record does not exist: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:24:47] [INFO]    [OmnipathR] Cache item `43ea5f2cdaa9ac7e0e114371af97235cdddd776f` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/43ea5f2cdaa9ac7e0e114371af97235cdddd776f-1.rds`.
[2025-03-18 20:24:47] [INFO]    [OmnipathR] Retrieving URL: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Attempt 1/3: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-18 20:24:47] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:25:08] [TRACE]   [OmnipathR] Downloaded 110.4 Kb in 21.062973s from rest.uniprot.org (5.2 Kb/s); Redirect: 0s, DNS look up: 0.001253s, Connection: 0.002276s, Pretransfer: 0.249684s, First byte at: 1.011869s
[2025-03-18 20:25:09] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/43ea5f2cdaa9ac7e0e114371af97235cdddd776f-1.rds`.
[2025-03-18 20:25:09] [INFO]    [OmnipathR] Download ready [key=43ea5f2cdaa9ac7e0e114371af97235cdddd776f, version=1]
[2025-03-18 20:25:09] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:25:09] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:25:09] [INFO]    [OmnipathR] Cache item `43ea5f2cdaa9ac7e0e114371af97235cdddd776f` version 1: status changed from `started` to `ready`.
[2025-03-18 20:25:09] [SUCCESS] [OmnipathR] UniProt (rest.uniprot.org): downloaded 17228 records
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Translating complexes: 0 complexes in data.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] 0 complexes after removing the ones mapping to more than 1 items in target identifier space.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Translated 0 complexes to 0.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] 13774 rows before translation, 13773 uniprot_entry IDs in column `id_organism_b`.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] 13774 rows after translation; translated 13273 `uniprot_entry` IDs in column `id_organism_b` to 13273 `uniprot` IDs in column `id_organism_b`.
[2025-03-18 20:25:10] [INFO]    [OmnipathR] Loaded database `Orthologous Matrix (OMA) gene pairs`.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] ID translation table: from `uniprot` to `genesymbol`, using `uniprot`.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Creating ID mapping table from `accession` to `gene_primary`, for organism 10090 (only reviewed: TRUE)
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Loading all UniProt records for organism 10090 (only reviewed: TRUE); fields: accession,gene_primary
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Looking up in cache: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`.
[2025-03-18 20:25:10] [INFO]    [OmnipathR] Cache record does not exist: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:25:10] [INFO]    [OmnipathR] Cache item `3ec84ba713c02573704adb50f1a94dab684df34b` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/3ec84ba713c02573704adb50f1a94dab684df34b-1.rds`.
[2025-03-18 20:25:10] [INFO]    [OmnipathR] Retrieving URL: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Attempt 1/3: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-18 20:25:10] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:25:24] [TRACE]   [OmnipathR] Downloaded 110.4 Kb in 14.06068s from rest.uniprot.org (7.9 Kb/s); Redirect: 0s, DNS look up: 0.00134s, Connection: 0.002249s, Pretransfer: 0.488099s, First byte at: 1.010759s
[2025-03-18 20:25:25] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/3ec84ba713c02573704adb50f1a94dab684df34b-1.rds`.
[2025-03-18 20:25:25] [INFO]    [OmnipathR] Download ready [key=3ec84ba713c02573704adb50f1a94dab684df34b, version=1]
[2025-03-18 20:25:25] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:25:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:25:25] [INFO]    [OmnipathR] Cache item `3ec84ba713c02573704adb50f1a94dab684df34b` version 1: status changed from `started` to `ready`.
[2025-03-18 20:25:25] [SUCCESS] [OmnipathR] UniProt (rest.uniprot.org): downloaded 17228 records
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Translating complexes: 0 complexes in data.
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] 0 complexes after removing the ones mapping to more than 1 items in target identifier space.
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Translated 0 complexes to 0.
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] 164184 rows before translation, 12877 uniprot IDs in column `uniprot`.
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] 164184 rows after translation; translated 12877 `uniprot` IDs in column `uniprot` to 12790 `genesymbol` IDs in column `genesymbol`.
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Arguments for OmniPath query: [dorothea_levels=[A,B,C,D],genesymbols=TRUE,organisms=9606,query_type=interactions,datasets=dorothea]
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:26] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:26] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:26] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:26] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:25:31] [TRACE]   [OmnipathR] Downloaded 3.3 Mb in 3.844527s from omnipathdb.org (885.7 Kb/s); Redirect: 0s, DNS look up: 0.001202s, Connection: 0.002272s, Pretransfer: 0.329323s, First byte at: 0.494888s
[2025-03-18 20:25:32] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:32] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:25:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:25:32] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:25:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:25:32] [INFO]    [OmnipathR] Cache item `46d37339bbc3f9a05bb89ccb79278cf1233f5cdf` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:25:32] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/46d37339bbc3f9a05bb89ccb79278cf1233f5cdf-1.rds`.
[2025-03-18 20:25:33] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/46d37339bbc3f9a05bb89ccb79278cf1233f5cdf-1.rds`.
[2025-03-18 20:25:33] [INFO]    [OmnipathR] Download ready [key=46d37339bbc3f9a05bb89ccb79278cf1233f5cdf, version=1]
[2025-03-18 20:25:33] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:25:33] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:25:33] [INFO]    [OmnipathR] Cache item `46d37339bbc3f9a05bb89ccb79278cf1233f5cdf` version 1: status changed from `started` to `ready`.
[2025-03-18 20:25:45] [SUCCESS] [OmnipathR] Downloaded 278830 interactions.
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Arguments for OmniPath query: [dorothea_levels=[A,B,C,D],genesymbols=TRUE,organisms=10090,query_type=interactions,datasets=dorothea]
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Organism(s): 10090
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:58] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:58] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:58] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:25:58] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:26:01] [TRACE]   [OmnipathR] Downloaded 2.9 Mb in 2.846401s from omnipathdb.org (1 Mb/s); Redirect: 0s, DNS look up: 0.001126s, Connection: 0.002348s, Pretransfer: 0.161581s, First byte at: 0.324677s
[2025-03-18 20:26:03] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-18 20:26:03] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:03] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:03] [INFO]    [OmnipathR] Cache item `ff347dedf78ef5e38c9c6d8eed291fa901aa3791` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:26:03] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/ff347dedf78ef5e38c9c6d8eed291fa901aa3791-1.rds`.
[2025-03-18 20:26:04] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/ff347dedf78ef5e38c9c6d8eed291fa901aa3791-1.rds`.
[2025-03-18 20:26:04] [INFO]    [OmnipathR] Download ready [key=ff347dedf78ef5e38c9c6d8eed291fa901aa3791, version=1]
[2025-03-18 20:26:04] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:04] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:04] [INFO]    [OmnipathR] Cache item `ff347dedf78ef5e38c9c6d8eed291fa901aa3791` version 1: status changed from `started` to `ready`.
[2025-03-18 20:26:16] [SUCCESS] [OmnipathR] Downloaded 234298 interactions.
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Arguments for OmniPath query: [loops=TRUE,organisms=9606,genesymbols=TRUE,query_type=interactions,datasets=collectri]
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:28] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:28] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:28] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:28] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:26:30] [TRACE]   [OmnipathR] Downloaded 1.5 Mb in 2.272661s from omnipathdb.org (655.8 Kb/s); Redirect: 0s, DNS look up: 0.001167s, Connection: 0.001994s, Pretransfer: 0.158934s, First byte at: 0.313959s
[2025-03-18 20:26:32] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:32] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:32] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:32] [INFO]    [OmnipathR] Cache item `b10176737ba43d460b13709623189f3911123779` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:26:32] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/b10176737ba43d460b13709623189f3911123779-1.rds`.
[2025-03-18 20:26:32] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/b10176737ba43d460b13709623189f3911123779-1.rds`.
[2025-03-18 20:26:32] [INFO]    [OmnipathR] Download ready [key=b10176737ba43d460b13709623189f3911123779, version=1]
[2025-03-18 20:26:32] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:32] [INFO]    [OmnipathR] Cache item `b10176737ba43d460b13709623189f3911123779` version 1: status changed from `started` to `ready`.
[2025-03-18 20:26:35] [SUCCESS] [OmnipathR] Downloaded 64958 interactions.
[2025-03-18 20:26:35] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:26:35] [TRACE]   [OmnipathR] Arguments for OmniPath query: [genesymbols=TRUE,resources=CollecTRI,strict_evidences=TRUE,query_type=interactions,datasets=tf_mirna]
[2025-03-18 20:26:35] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-18 20:26:35] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:26:36] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:26:36] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:36] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:36] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:36] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:36] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:36] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:36] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:36] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:36] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,tcp_keepcnt=13,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-03-18 20:26:37] [TRACE]   [OmnipathR] Downloaded 9.5 Kb in 0.238546s from omnipathdb.org (39.8 Kb/s); Redirect: 0s, DNS look up: 0.001025s, Connection: 0.001821s, Pretransfer: 0.160208s, First byte at: 0.238274s
[2025-03-18 20:26:38] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:38] [INFO]    [OmnipathR] Cache item `f7d34500401ba98803b7d2b26c48f64cee1eea1b` version 1: status changed from `unknown` to `started`.
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] Exporting object to RDS: `/Users/biocbuild/Library/Caches/OmnipathR/f7d34500401ba98803b7d2b26c48f64cee1eea1b-1.rds`.
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] Exported RDS to `/Users/biocbuild/Library/Caches/OmnipathR/f7d34500401ba98803b7d2b26c48f64cee1eea1b-1.rds`.
[2025-03-18 20:26:38] [INFO]    [OmnipathR] Download ready [key=f7d34500401ba98803b7d2b26c48f64cee1eea1b, version=1]
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] Reading JSON from `/Users/biocbuild/Library/Caches/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:38] [INFO]    [OmnipathR] Cache item `f7d34500401ba98803b7d2b26c48f64cee1eea1b` version 1: status changed from `started` to `ready`.
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] Converting JSON column `evidences` to list.
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] Restricting interaction records to datasets: tf_mirna; and resources: CollecTRI
[2025-03-18 20:26:38] [TRACE]   [OmnipathR] Filtering evidence columns: positive, negative, directed, undirected; to datasets: tf_mirna; and resources: CollecTRI; excluding resources: none
[2025-03-18 20:26:39] [SUCCESS] [OmnipathR] Downloaded 232 interactions.
[2025-03-18 20:26:39] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:26:39] [TRACE]   [OmnipathR] Arguments for OmniPath query: [loops=TRUE,organisms=9606,genesymbols=TRUE,query_type=interactions,datasets=collectri]
[2025-03-18 20:26:39] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-18 20:26:39] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:26:39] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:39] [TRACE]   [OmnipathR] Loaded data from RDS `/Users/biocbuild/Library/Caches/OmnipathR/b10176737ba43d460b13709623189f3911123779-1.rds`.
[2025-03-18 20:26:39] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-18 20:26:42] [SUCCESS] [OmnipathR] Loaded 64958 interactions from cache.
[2025-03-18 20:26:42] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-18 20:26:42] [TRACE]   [OmnipathR] Arguments for OmniPath query: [genesymbols=TRUE,resources=CollecTRI,strict_evidences=TRUE,query_type=interactions,datasets=tf_mirna]
[2025-03-18 20:26:42] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-18 20:26:42] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-18 20:26:43] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-18 20:26:43] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-18 20:26:43] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:43] [TRACE]   [OmnipathR] Loaded data from RDS `/Users/biocbuild/Library/Caches/OmnipathR/f7d34500401ba98803b7d2b26c48f64cee1eea1b-1.rds`.
[2025-03-18 20:26:43] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-18 20:26:43] [TRACE]   [OmnipathR] Converting JSON column `evidences` to list.
[2025-03-18 20:26:43] [TRACE]   [OmnipathR] Restricting interaction records to datasets: tf_mirna; and resources: CollecTRI
[2025-03-18 20:26:43] [TRACE]   [OmnipathR] Filtering evidence columns: positive, negative, directed, undirected; to datasets: tf_mirna; and resources: CollecTRI; excluding resources: none
[2025-03-18 20:26:44] [SUCCESS] [OmnipathR] Loaded 232 interactions from cache.

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Attaching package: 'dplyr'

The following object is masked from 'package:testthat':

    matches

The following objects are masked from 'package:stats':

    filter, lag

The following objects are masked from 'package:base':

    intersect, setdiff, setequal, union

[ FAIL 0 | WARN 9 | SKIP 0 | PASS 35 ]

[ FAIL 0 | WARN 9 | SKIP 0 | PASS 35 ]
> 
> proc.time()
   user  system elapsed 
172.561  20.743 317.092

Example timings

decoupleR.Rcheck/decoupleR-Ex.timings

name	user	system	elapsed
check_corr	0.088	0.015	0.107
convert_f_defaults	0.031	0.004	0.035
decouple	0.002	0.002	0.005
dot-fit_preprocessing	0.028	0.004	0.031
extract_sets	0.026	0.001	0.028
filt_minsize	0.052	0.001	0.053
get_collectri	8.993	1.241	19.038
get_dorothea	25.954	1.994	31.030
get_profile_of	0.000	0.001	0.001
get_progeny	5.905	0.701	29.288
get_resource	0.749	0.113	2.638
get_toy_data	0.003	0.001	0.004
intersect_regulons	0.036	0.009	0.046
pipe	0	0	0
pivot_wider_profile	0.000	0.000	0.001
randomize_matrix	0	0	0
rename_net	0.05	0.01	0.06
run_aucell	12.152	4.511	16.731
run_consensus	2.740	0.665	4.085
run_fgsea	20.953	1.319	22.579
run_gsva	2.641	1.157	3.972
run_mdt	0.252	0.063	0.327
run_mlm	0.121	0.021	0.142
run_ora	0.721	0.111	0.841
run_udt	0.390	0.061	0.451
run_ulm	0.100	0.020	0.121
run_viper	1.195	0.565	1.778
run_wmean	0.964	0.111	1.117
run_wsum	0.906	0.121	1.271
show_methods	0.068	0.018	0.092
show_resources	0.063	0.009	0.681
tidyeval	0	0	0